Which pair do you think really locks in perfectly, complements each other, seems to have an almost telepathic relationship and came up with a wonderful sound? A couple of my favourites: John Frusciante and Flea Steve Howe and Chris Squire
Pete Townshend and John Entwistle Johnny Marr and Andy Rourke Alex Lifeson and Geddy Lee David Gilmour and Roger Waters
DING! DING! DING! Winner! Trying to think of another that have made music together for half a century often as a duo.
Howe / Squire for sure Anastasio / Gordon (Phish) Phil / Jerry (Grateful Dead) George Porter Jr. / Leo Nocentelli (The Meters)
Nile Rodgers and Bernard Edwards of Chic. Their lock on Good Times would be enough, but they literally played in perfect simpatico on dozens of tracks.