As a physicist (dim distant past), I could never come to a solid understanding of why a bunch of decently-made speaker cables can sound different. As an audio-dude (longer career than physicist), I'm in no doubt. However, cable vs cable seems to me to be the wrong argument. I have consistently found that 'cable+component' vs 'cable+component' is the really effective mode of comparison. I've had expensive Kimber Monocle XL monster cables be embarrassed by Home Depot solid core wire, on one particular set of speakers. Another speaker type created a diametrically opposite synergy, with the Kimber sounding like it's worth every penny. I think synergy is the game and I'm not convinced that any one particular design or price tag can easily be considered 'better' outside of consideration of the speakers, and by inference, the amplifier too.