Or ALMOST killed them. Or damaged them so severely that we can say there was a career comeback later. Use your own judgment. You just get more internet points if it was a clean kill. Actors, directors, producers, etc. all eligible. Heaven's Gate - Michael Cimino. A director's career death. A career killer is not necessarily the last item on the resume, but is a severe injury that starts a bleeding the patient never recovers from. Jade - David Caruso - Killed his attempt at a film career. A William Friedkin/Joe Eszterhas thriller that flopped and sent Caruso back to TV. Last Action Hero was considered the first major misfire in Arnold's career. He recovered nicely with True Lies, but it exposed a vulnerability that never really healed. He would have far more misfires than hits throughout the rest of his career. Hollywood Homicide - a double career killer for director Ron Shelton and Harrison Ford. Harrison had been soaring to great heights in the '90s but K19 and Homicide were back-to-back flops. K19 could be seen as an overall miscalculation but Homicide wasn't as excusable. It was designed to be purely commercial. Ford essentially never recovered after this, only retaining a high profile by doing sequels to his big 1980s hits. Shelton had a couple flops before this, but nothing so high profile and big budget. It would be 14 years before the director of Bull Durham and White Men Can't Jump would direct another feature film (which also flopped). Catwoman - Halle Berry. This was like hitting a brick wall at 90 miles an hour after X-Men 1 and 2, Swordfish, Die Another Day, Gothika and her Oscar win for Monster's Ball. Other than finishing up her X-Men cameos, her movie career has gotten downright shabby and ragged since Catwoman. Catwoman also did no favors for... Sharon Stone, who two years later made Basic Instinct 2. Stone's career has been a giant mess of hits and flops, full of Golden Globe, Oscar and Razzie recognition. Her career had all but bled out by the time of Basic Instinct 2, but it was the final ice pick in the chest. After this, mainstream Hollywood basically said the second chances are over and she's been, perhaps happily, working only in low-budget, independent films. Troop Beverly Hills - Shelley Long. This was the one where everyone finally knew for sure Shelley had made the wrong decision to leave Cheers. If there was any doubt left, Frozen Assets put it to rest three years later. Yes, she had a dead cat bounce with The Brady Bunch, but in a supporting role and not something that could be called a comeback or led to bigger roles. Dana Carvey - Master of Disguise. This was essentially a second chance after doing 3 movies in 1994 that all flopped. The box office on Master wasn't even that disastrous. But when you star in something that's considered one of the worst movies ever made, it doesn't give people a lot of confidence in you. This was it for Carvey. Only voice-acting roles from then on. Mike Myers - The Love Guru. It's not truly over for Myers. Hollywood would give him another chance starring in a comedy, like Dr. Evil: The Movie or Wayne's World 3, maybe even something original. He's gotten praise for supporting work after this. But this notorious flop seems to have been a self-inflicted death blow. Myers has lost the confidence in himself to attempt a major comeback. Chevy Chase - Vegas Vacation - Chevy had been in trouble for a while, but his last film before this, Man of the House, was a bit of a box office comeback for him. But Vegas Vacation cost more and did worse. Chevy's career essentially died with his number one franchise here. The resume from this point on is a nightmare. Dan Aykroyd - Nothing But Trouble - This directorial debut killed Dan's directing career in one shot and did no favors for his acting career or anyone else's involved. Arguably his acting career got its death blow a bit later with... Exit to Eden - A disastrously ill-conceived movie that may qualify as a career killer for Dan Aykroyd, Dana Delany and Rosie O'Donnell. Dan may have gotten a couple more decent parts after this, but the public no longer saw him as a box office draw and they weren't successful. And if there was any doubt, Blues Brothers 2000 was the final nail in the coffin. Eddie Murphy - Norbit - Eddie's career had lost its heart and soul long before this, but was still doing reasonable box office. But this movie was so disastrously ill-timed after his minor creative comeback with Dreamgirls. It did okay box office, but was the last thing anyone rooting for him wanted to see at this point. This kicked off a particularly bad triple threat of movies with director Brian Robbins (Eric on TV's Head of the Class) that also included the instantly obscure Meet Dave and A Thousand Words. Eddie's post-Dreamgirls career is a huge missed opportunity that I don't think a desperate attempt at a non-theatrical sequel to one of his biggest 1980s hits will rectify. The Adventures of Pluto Nash - A 2002 disaster that didn't quite end Eddie's career, but sent director Ron Underwood to director's jail. The director of Tremors, City Slickers and Mighty Joe Young would be relegated to TV and one low-budget feature after this. Cruising - Razzie noms, controversy, weak box office and essentially the end of director William Friedkin's star director status. Waterworld - It was NOT a death blow to Costner, but it definitely put Kevin Reynolds in director's jail. The big budgets and high-profile projects wouldn't come his way again. The Sorcerer's Apprentice - It's hard to pinpoint but this appears to be the point at which Nicolas Cage's career lost its last remaining shreds of dignity and credibility. Jack Frost - This was the end of Michael Keaton's credibility as a movie star for a long time until his genuine comeback in Birdman 16 years later. Battlefield Earth - John Travolta. Nuff said.